Conditions like Postural Orthostatic Tachycardia Syndrome (POTS) and Mast Cell Activation Syndrome (MCAS)often co-occur with ALPIMS traits, creating overlapping storms of dysregulation. These are not “rare flukes”—they are clues that the nervous and immune systems are overreactive and under-supported.
Regulation is possible when the body feels safe enough to shift out of survival mode.
How POTS and MCAS Relate to ALPIMS
| System | POTS/MCAS Feature | ALPIMS Domain Link |
|---|---|---|
| Autonomic | Heart rate spikes, dizziness, fatigue | Laxity, Anxiety |
| Vascular | Flushing, blood pooling, lightheadedness | Pain, Sensory |
| Immune | Histamine surges, rashes, GI symptoms | Immune, Sensory |
| Endocrine | Crashes after exertion, temperature swings | Mood, Pain |
| Neurological | Brain fog, overstimulation, panic | Anxiety, Sensory, Mood |
These conditions reflect impaired homeostasis and “stuck” Cell Danger Response (CDR) states. Stabilizing one domain helps others regulate too.
Regulation Strategies by System
Nervous System (POTS, Overwhelm, Sensory Dysregulation)
- Daily vagal toning: gentle hums, long exhales, cold water splash
- Positional pacing: recline > stand, avoid fast transitions
- Sensory scaffolding: low light, noise buffers, structured transitions
- Slow nervous input: weighted blankets, pressure garments, grounding touch
Immune System (MCAS, Food Sensitivity, Flare Triggers)
- Low-histamine, low-additive diet
- Supplements with care: quercetin, vitamin C, DAO (medical advice required)
- Filter your environment: air purifiers, non-toxic cleaners, avoid strong scents
- Titrate exposures: sunlight, new foods, smells—start small, observe zone
Cross-System Regulation
- Zone tracking: log symptoms, triggers, and recoveries in ALPIMS format
- Compression wear: socks, garments to support circulation and proprioception
- Salt + hydration protocols: if tolerated, balance fluid/sodium intake
- Movement as medicine: stretching, recumbent motion, somatic resets
Helpful Templates & Downloads
POTS + MCAS Zone Tracker Trigger–Response–Recovery Log Symptom Interaction Wheel: ALPIMS + Dysautonomia Nervous–Immune Daily Care Planner
[Download: Full Nervous–Immune Regulation Toolkit] [Explore: Low-Stim Meal Plans, Emergency Flare Cards, and Soothing Routines]
You’re not too sensitive. You’re exquisitely attuned to a body asking for safety.
With consistency, compassion, and custom pacing, the system can rebuild tolerance.