In our family we began noticing a pattern.
Different family members were diagnosed with different health conditions, including:
- migraine spectrum conditions
- hypermobility spectrum conditions
- ME/CFS spectrum illness
- fibromyalgia and chronic pain
- autism and sensory processing differences
At first these diagnoses seemed unrelated.
But over time we began noticing many similar patterns of symptoms, including fatigue, pain, sensory sensitivity, nervous system overload, and fluctuating health.
This made us wonder whether something underneath these conditions might be connected.
As we learned more, we discovered that many of these conditions appear to involve overlapping regulation sensitivities in the body.
These sensitivities can affect several systems at once, including the nervous system, connective tissue, immune responses, sensory processing, and emotional regulation.
In our family, these patterns seemed to span six areas:
Autonomic • Laxity • Pain • Immune • Mood • Sensory
We began referring to these overlapping domains as ALPIMS.
Understanding these connections helped us make sense of symptoms that once felt confusing and disconnected.
Instead of focusing only on individual diagnoses, we began looking at ways to support the body’s overall regulation and capacity.
This website shares the ideas, insights, and practical strategies that helped our family navigate these overlapping sensitivities.

Learn more: Overlapping Spectrum Disorders and ALPIMS


