Mast Cell activation Syndrome (MCAS) is a condition that is underappreciated for its role in neuropsychiatric symptoms (anxiety and mood).
MCAS is an immune condition that is over represented in laxity related connective tissue disorders like ESD. See Laxity and immune to learn more about MCAS.
Mood can also be simply impacted by living with a complex medical conditions that can potentially impact every aspect of life, and also energy.
