Laxity

Hypermobility, characterized by overly flexible joints, is more common among individuals with autism spectrum disorder (ASD) compared to the general population.234+5 This condition can lead to chronic pain, joint instability, and fatigue, and it is often associated with connective tissue disorders such as Ehlers-Danlos Syndrome (EDS).235+2 Research indicates that over 50% of participants diagnosed with ASD exhibit hypermobility, compared to just 20% of the general population.468 The exact nature of the link between hypermobility and autism is not fully understood, but it is believed that both conditions may share underlying mechanisms related to connective tissue development and function.59 Additionally, hypermobility is often accompanied by sensory hypersensitivities and autonomic dysfunction, which are also common in individuals with autism.257+2 Understanding this connection can help in developing more comprehensive care and management strategies for individuals with ASD.69

• Hypermobility Spectrum Disorders (HSD): These are genetic connective tissue disorders that affect joints and ligaments, and are more prevalent in individuals with autism.79
• Ehlers-Danlos Syndrome (EDS): This genetic syndrome affects the connective tissues of the body, including bones, skin, blood vessels, and other organs. It is commonly associated with autism, and individuals with EDS are 7.4 times more likely to be autistic.257+1

Further research is needed to fully comprehend the relationship between hypermobility and autism and its implications for people living with autism.